EpCAM is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.

Reference: http://www.ncbi.nlm.nih.gov/gene/4072

Assay type: Immunohistochemistry (IHC)
What is analyzed: Semi-quantitative detection of Epithelial cell adhesion molecule (EpCAM)
Platform: DAKO Autostainer Plus
Kit/antibody: NCL-ESA (NOVOCASTRA)
Tissue Type: All tissues
Required material: FFPE tissue